SCHEMBL83935

SCHEMBL83935

O=C(OCCO)ON1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13464052 0.90 MEN1 (0.37) TSHR
SCHEMBL13464062 0.90 MEN1 (0.37) TSHR
SCHEMBL18755724 0.89 ALOX12 (0.33) ALOX12
SCHEMBL11998879 0.87 ALOX12 (0.35) ALOX12
SCHEMBL23608353 0.87 ALOX12 (0.30) ALOX12MGLL
SCHEMBL11989407 0.85 ALDH1A1 (0.32) TSHRALOX12MGLL
SCHEMBL29842557 0.85 ALDH1A1 (0.32) TSHRALOX12MGLL
SCHEMBL1949595 0.85 ALOX12 (0.38) TSHRALOX12MGLL
SCHEMBL13748507 0.85 ALOX12 (0.38) TSHRALOX12MGLL
Ethylene Glycol SCHEMBL8522385 0.84 MGLL (0.33) ALOX12MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238480-A1 DEVICES FOR IN SITU FORMED NERVE CAPS AND/OR NERVE WRAPS TULAVI THERAPEUTICS INC (US) 2024-07-18 US claimed
CN-118105543-A Vancomycin-carrying hydrogel porous surgical implant for treating infectious bone defect and preparation method thereof 山东大学齐鲁医院 2024-05-31 CN claimed
US-11944717-B2 Devices for in situ formed nerve caps and/or nerve wraps Tulavi Therapeutics, Inc. (US) 2024-04-02 US claimed
CN-112638437-B Method and apparatus for forming nerve caps in situ 图拉维治疗股份有限公司 2023-12-08 CN claimed
CN-115361912-A Method and apparatus for in situ formation of a nerve cap with quick release 图拉维治疗股份有限公司 2022-11-18 CN claimed
US-20220054705-A1 DEVICES FOR IN SITU FORMED NERVE CAPS AND/OR NERVE WRAPS Tulavi Therapeutics, Inc. 2022-02-24 US claimed
CN-110251731-B Islet cell microcapsule for tissue engineering and preparation method thereof 山东百多安医疗器械股份有限公司 2021-09-03 CN claimed
CN-110201234-B Prostate cell microcapsule for tissue engineering and preparation method thereof 山东百多安医疗器械股份有限公司 2021-09-03 CN claimed
WO-2021146330-A1 METHODS AND DEVICES FOR IN SITU FORMED NERVE CAP WITH RAPID RELEASE Tulavi Therapeutics, Inc. (US) 2021-07-22 WO claimed
CN-112638437-A Method and apparatus for forming a nerve cap in situ 图拉维治疗股份有限公司 2021-04-09 CN claimed
EP-0994959-A1 POLYMER-MODIFIED VIRUSES GENZYME CORPORATION (US) 2000-04-26 EP claimed
WO-2000011202-A1 CATIONIC COMPLEXES OF POLYMER-MODIFIED ADENOVIRUS GENZYME CORPORATION (US) 2000-03-02 WO claimed
JP-2907300-B2 1999-06-21 JP claimed
WO-1998044143-A9 POLYMER-MODIFIED VIRUSES GENZYME CORP (US) 1999-04-22 WO claimed
WO-1998044143-A1 POLYMER-MODIFIED VIRUSES GENZYME CORPORATION (US) 1998-10-08 WO claimed
US-5620884-A MODIFIED POLYETHER ENZON, INC. (US) 1997-04-15 US claimed
US-5386014-A Reducing and deoxygenating bovine hemoglobin; conjugation to activated polyalkylene oxide in presence of chloride anions ENZON, INC. (US) 1995-01-31 US claimed
EP-0502113-A4 CHEMICALLY MODIFIED HEMOGLOBIN AS AN EFFECTIVE, STABLE, NON-IMMUNOGENIC RED BLOOD CELL SUBSTITUTE 1993-03-31 EP claimed
EP-0502113-A1 CHEMICALLY MODIFIED HEMOGLOBIN AS AN EFFECTIVE, STABLE, NON-IMMUNOGENIC RED BLOOD CELL SUBSTITUTE ENZON, INC. (US) 1992-09-09 EP claimed
WO-1991007190-A1 CHEMICALLY MODIFIED HEMOGLOBIN AS AN EFFECTIVE, STABLE, NON-IMMUNOGENIC RED BLOOD CELL SUBSTITUTE ENZON, INC. (US) 1991-05-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11944717-B2 Devices for in situ formed nerve caps and/or nerve wraps GAP43, NGF, CAPG TSHR 3914/4885ALOX12 4051/4885MGLL 2639/4885
US-20240238480-A1 DEVICES FOR IN SITU FORMED NERVE CAPS AND/OR NERVE WRAPS GAP43, NGF, CAPG TSHR 3914/4885ALOX12 4051/4885MGLL 2639/4885
US-20220054705-A1 DEVICES FOR IN SITU FORMED NERVE CAPS AND/OR NERVE WRAPS GAP43, NGF, CAPG TSHR 3901/4885ALOX12 4047/4885MGLL 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.