Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397068 | 0.88 | CYP1A2 (0.35) | CYP1A2SIGMAR1RENMEN1KMT2A | |
| SCHEMBL6564732 | 0.79 | RELA (0.38) | CYP1A2RENCA1CA2CA12 | |
| SCHEMBL8395547 | 0.77 | SIGMAR1 (0.48) | CYP1A2SIGMAR1RENBMP1ALDH1A1 | |
| SCHEMBL8392865 | 0.77 | SIGMAR1 (0.48) | CYP1A2SIGMAR1RENBMP1ALDH1A1 | |
| SCHEMBL8392560 | 0.75 | ADH1B (0.40) | KMT2AALDH1A1EPHX1 | |
| SCHEMBL8395807 | 0.74 | GRIA1 (0.57) | CYP1A2SIGMAR1RENBMP1 | |
| SCHEMBL4071690 | 0.74 | POLB (0.40) | CYP1A2SIGMAR1BMP1CA1CA2 | |
| SCHEMBL31593692 | 0.73 | SIGMAR1 (0.48) | CYP1A2SIGMAR1RENMEN1KMT2A | |
| SCHEMBL8392349 | 0.71 | SAT1 (0.52) | CYP1A2SIGMAR1MEN1KMT2A | |
| SCHEMBL17664608 | 0.71 | CYP1A2 (0.34) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |