Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398440 | 0.88 | GRIN2D (0.41) | TBXA2RGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8397457 | 0.84 | MAPT (0.46) | TBXA2RHSPB1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8397454 | 0.82 | ALDH1A1 (0.46) | TBXA2RHSPB1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8394842 | 0.82 | TBXA2R (0.48) | TBXA2RHSPB1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8398648 | 0.81 | TBXA2R (0.51) | TBXA2RGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8398452 | 0.81 | TDP1 (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8398658 | 0.79 | ALDH1A1 (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL22966296 | 0.79 | TBXA2R (0.56) | TBXA2RHSPB1MAPTNPSR1CYP1A2 | |
| SCHEMBL8395390 | 0.77 | PDE7A (0.48) | TBXA2RHSPB1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8398691 | 0.77 | TBXA2R (0.46) | TBXA2RHSPB1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994563-A | THIOPHENE DERIVATIVES, IMMUNOSUPPRESSANTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1999-11-30 | — | — | US | disclosed |