Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394842 | 0.88 | TBXA2R (0.48) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL8398648 | 0.85 | TBXA2R (0.51) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL8398691 | 0.83 | TBXA2R (0.46) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29380207 | 0.83 | TBXA2R (0.46) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8395390 | 0.83 | PDE7A (0.48) | ALDH1A1TDP1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8397457 | 0.83 | MAPT (0.46) | ALDH1A1TDP1TSHRLMNAHPGD | |
| SCHEMBL8398681 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTHPGDSMN1; SMN2 | |
| SCHEMBL8394756 | 0.83 | CES2 (0.41) | ALDH1A1HTTKMT2AMEN1POLB | |
| SCHEMBL8395016 | 0.82 | TBXA2R (0.49) | ALDH1A1TDP1TSHRLMNAHTT | |
| SCHEMBL8398440 | 0.82 | GRIN2D (0.41) | ALDH1A1TDP1TSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994563-A | THIOPHENE DERIVATIVES, IMMUNOSUPPRESSANTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1999-11-30 | — | — | US | disclosed |