Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394842 | 0.88 | TBXA2R (0.48) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29380207 | 0.88 | TBXA2R (0.46) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8398691 | 0.88 | TBXA2R (0.46) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8395390 | 0.88 | PDE7A (0.48) | MAPTLMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL8398648 | 0.87 | TBXA2R (0.51) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8398722 | 0.86 | LMNA (0.52) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8394756 | 0.84 | CES2 (0.41) | MAPTALDH1A1MEN1KMT2ATBXA2R | |
| SCHEMBL8398681 | 0.84 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8397467 | 0.84 | MERTK (0.46) | MAPTALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL8399971 | 0.84 | HSPB1 (0.43) | MAPTLMNAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994563-A | THIOPHENE DERIVATIVES, IMMUNOSUPPRESSANTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1999-11-30 | — | — | US | disclosed |