Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.73 |
| ▸ | HEXA | P06865 | 14/20 | 0.66 |
| ▸ | HEXB | P07686 | 14/20 | 0.66 |
| ▸ | OGA | O60502 | 2/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Elinafide SCHEMBL6256967 | 0.85 | SIRT1 (1.00) | SIRT1HEXAHEXBOGA | |
| Elinafide SCHEMBL29441732 | 0.85 | SIRT1 (1.00) | SIRT1HEXAHEXBOGA | |
| Elinafide SCHEMBL19067 | 0.85 | SIRT1 (1.00) | SIRT1HEXAHEXBOGA | |
| SCHEMBL8393452 | 0.85 | SIRT1 (0.73) | SIRT1HEXAHEXBOGA | |
| SCHEMBL8396162 | 0.82 | SIRT1 (0.94) | SIRT1HEXAHEXBOGA | |
| SCHEMBL3290712 | 0.82 | SIRT1 (0.86) | SIRT1HEXAHEXBOGA | |
| SCHEMBL14524900 | 0.82 | SIRT1 (0.86) | SIRT1HEXAHEXBOGA | |
| SCHEMBL31011151 | 0.81 | HEXA (1.00) | SIRT1HEXAHEXBOGA | |
| SCHEMBL4408773 | 0.81 | HEXA (1.00) | SIRT1HEXAHEXBOGA | |
| Elinafide SCHEMBL1890262 | 0.81 | SIRT1 (0.84) | SIRT1HEXAHEXBOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981753-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| EP-0714387-B1 | NEW BIS-NAPHTHALIMIDES FOR THE TREATMENT OF CANCER | BASF AG (DE) | 1998-05-27 | — | — | EP | disclosed |
| US-5616589-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0714387-A1 | NEW BIS-NAPHTHALIMIDES FOR THE TREATMENT OF CANCER | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005365-A1 | NEW BIS-NAPHTHALIMIDES FOR THE TREATMENT OF CANCER | BASF AKTIENGESELLSCHAFT (DE) | 1995-02-23 | — | — | WO | disclosed |