Sugi Predict

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Elinafide

Elinafide

SCHEMBL29441732

O=C1c2cccc3cccc(c23)C(=O)N1CCNCCCNCCN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SIRT1 Q96EB6 3/20 1.00
▸ HEXA P06865 14/20 0.90
▸ HEXB P07686 14/20 0.90
▸ OGA O60502 1/20 0.90
▸ MEN1 O00255 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ NR1I2 O75469 1/20 0.57
▸ POLB P06746 1/20 0.57
▸ AHR P35869 1/20 0.57
▸ RAD52 P43351 1/20 0.57
▸ RCE1 Q9Y256 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Elinafide SCHEMBL6256967 1.00 SIRT1 (1.00) SIRT1HEXAHEXBOGAMEN1
Elinafide SCHEMBL19067 1.00 SIRT1 (1.00) SIRT1HEXAHEXBOGAMEN1
SCHEMBL8396162 0.97 SIRT1 (0.94) SIRT1HEXAHEXBOGAMEN1
SCHEMBL31011151 0.95 HEXA (1.00) SIRT1HEXAHEXBOGA
SCHEMBL4408773 0.95 HEXA (1.00) SIRT1HEXAHEXBOGA
Bnipdpta SCHEMBL13909966 0.94 SIRT1 (0.88) SIRT1HEXAHEXBOGAMEN1
SCHEMBL13909979 0.94 SIRT1 (0.88) SIRT1HEXAHEXBOGAMEN1
SCHEMBL3290712 0.93 SIRT1 (0.86) SIRT1HEXAHEXBOGA
SCHEMBL14524900 0.93 SIRT1 (0.86) SIRT1HEXAHEXBOGANR1I2
Bnipspd SCHEMBL13909975 0.92 SIRT1 (0.91) SIRT1HEXAHEXBOGAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027226-A1 ANTIBODY-DRUG CONJUGATES PHEON THERAPEUTICS LTD (GB) 2026-01-29 — — US disclosed
EP-4658315-A1 POLYMER-DRUG CONJUGATES Primelink Biotherapeutics (Shenzhen) Co., Ltd. (CN) 2025-12-10 — — EP disclosed
WO-2025149667-A1 ANTIBODY DRUG CONJUGATES AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2025-07-17 — — WO disclosed
US-20250205356-A1 POLYMER-DRUG CONJUGATES PRIMELINK BIOTHERAPEUTICS (SHENZHEN) CO., LTD (CN) 2025-06-26 — — US disclosed
EP-4554624-A1 ANTIBODY-DRUG CONJUGATES Pheon Therapeutics Ltd (GB) 2025-05-21 — — EP disclosed
EP-4554623-A1 ANTIBODY DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF Pheon Therapeutics Ltd (GB) 2025-05-21 — — EP disclosed
EP-4496823-A1 POLYMER-DRUG CONJUGATES Primelink Biotherapeutics (Shenzhen) Co., Ltd (CN) 2025-01-29 — — EP disclosed
US-20240382611-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2024-11-21 — — US disclosed
WO-2024160202-A1 POLYMER-DRUG CONJUGATES PRIMELINK BIOTHERAPEUTICS (SHENZHEN) CO., LTD. (CN) 2024-08-08 — — WO disclosed
US-11964025-B2 Peptide-containing linkers for antibody-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2024-04-23 — — US disclosed
CN-115109033-B Synthesis and bioactivity research of 1, 8-naphthalimide derivative 河南师范大学 2023-11-14 — — CN disclosed
WO-2023179521-A1 POLYMER-DRUG CONJUGATES PRIMELINK BIOTHERAPEUTICS (SHENZHEN) CO., LTD (CN) 2023-09-28 — — WO disclosed
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES ASANA BIOSCIENCES, LLC 2023-06-15 — — US disclosed
US-20230043447-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2023-02-09 — — US disclosed
US-20230021500-A1 CYSTEINE ENGINEERED ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS MERSANA THERAPEUTICS, INC. 2023-01-26 — — US disclosed
CN-115109033-A Synthesis and biological activity research of 1, 8-naphthalimide derivative 河南师范大学 2022-09-27 — — CN disclosed
CN-115068626-A Protein-polymer-drug conjugates 阿萨纳生物科技有限责任公司 2022-09-20 — — CN disclosed
US-11434278-B2 Protein-polymer-drug conjugates ASANA BIOSCIENCES, LLC (US) 2022-09-06 — — US disclosed
CN-114773424-A Nanolong derivative with biological activity and preparation method and application thereof 济南爱思医药科技有限公司 2022-07-22 — — CN disclosed
CN-105813655-B Protein-polymer-drug conjugates 阿萨纳生物科技有限责任公司 2022-03-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, STAMBP, TSPO SIRT1 2541/4885HEXA 3350/4885HEXB 3664/4885
US-20250205356-A1 POLYMER-DRUG CONJUGATES ILK, ECPAS, MSN SIRT1 1988/4885HEXA 1846/4885HEXB 3038/4885
US-20230021500-A1 CYSTEINE ENGINEERED ANTIBODY-DRUG CONJUGATES WITH PEPTIDE-CONTAINING LINKERS LNPEP, DNPEP, QPCT SIRT1 3985/4885HEXA 2771/4885HEXB 2621/4885
US-20230043447-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES CD2BP2, DNPEP, LNPEP SIRT1 4075/4885HEXA 2241/4885HEXB 2054/4885
US-20240382611-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES CD2BP2, DNPEP, LNPEP SIRT1 4075/4885HEXA 2241/4885HEXB 2054/4885
US-11964025-B2 Peptide-containing linkers for antibody-drug conjugates CD2BP2, DNPEP, LNPEP SIRT1 4075/4885HEXA 2241/4885HEXB 2054/4885
US-11434278-B2 Protein-polymer-drug conjugates PBRM1, STAMBP, TSPO SIRT1 2541/4885HEXA 3350/4885HEXB 3664/4885
US-20260027226-A1 ANTIBODY-DRUG CONJUGATES SLC3A2, MTCL3, SLC13A2 SIRT1 3965/4885HEXA 4773/4885HEXB 4841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.