Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400239 | 0.92 | SMN1; SMN2 (0.51) | MTNR1AMTNR1BSMN1; SMN2TDP1MAPT | |
| SCHEMBL8396222 | 0.91 | SMN1; SMN2 (0.43) | MTNR1AMTNR1BSMN1; SMN2MAPTKDM4E | |
| SCHEMBL8400465 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL8396315 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2TDP1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8396079 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTALDH1A1TSHRMAPK1 | |
| SCHEMBL8395385 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2TDP1MAPTALDH1A1TSHR | |
| SCHEMBL8399213 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2TDP1KDM4EPTGDR2MEN1 | |
| SCHEMBL8399172 | 0.86 | LTB4R2 (0.45) | SMN1; SMN2MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL8399265 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTALDH1A1MAPK1KMT2A | |
| SCHEMBL8400205 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |