SCHEMBL8396205

SCHEMBL8396205

CCOC(=O)C1=C(c2ccccc2)C(=O)N=N1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 1/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TSHR P16473 1/20 0.46
HPGDS O60760 1/20 0.46
ADORA3 P0DMS8 2/20 0.46
PPARG P37231 1/20 0.45
CDC7 O00311 1/20 0.45
TRPM8 Q7Z2W7 1/20 0.45
DBF4 Q9UBU7 1/20 0.45
MAPK1 P28482 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7759462 0.77 ALOX5 (0.44) KDM4EALDH1A1LMNAMAPTRAB9A
SCHEMBL14000243 0.76 PPARG (0.53) KDM4EALDH1A1LMNAMAPTRAB9A
SCHEMBL8359086 0.74 PPARG (0.63) KDM4EALDH1A1LMNAMAPTRAB9A
SCHEMBL7300958 0.73 ALDH1A1 (0.49) KDM4EALDH1A1LMNAMAPTRAB9A
SCHEMBL7306231 0.73 ALDH1A1 (0.49) KDM4EALDH1A1LMNAMAPTRAB9A
SCHEMBL182947 0.73 PDE4B (0.42) ALDH1A1LMNAMAPTGAANPSR1
SCHEMBL28509371 0.72 PPARG (0.56) KDM4EALDH1A1LMNAMAPTRAB9A
SCHEMBL11777448 0.70 ALDH1A1 (0.43) KDM4EALDH1A1LMNAMAPTRAB9A
SCHEMBL17969781 0.70 ALDH1A1 (0.78) KDM4EALDH1A1LMNAMAPTRAB9A
SCHEMBL7538581 0.70 PPARG (0.72) KDM4EALDH1A1LMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0914386-A1 PIGMENT COMPOSITIONS Engelhard Corporation (US) 1999-05-12 EP disclosed
WO-1997045493-A1 PIGMENT COMPOSITIONS ENGELHARD CORPORATION (US) 1997-12-04 WO disclosed