Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399047 | 0.91 | GRM5 (0.39) | HIF1ASMN1; SMN2L3MBTL1KDM4EMAPT | |
| SCHEMBL8399231 | 0.88 | HIF1A (0.44) | HIF1AKMT2AMAOBMEN1 | |
| SCHEMBL8400501 | 0.88 | FFAR1 (0.40) | HIF1AKMT2AKDM4EMAPTMAOB | |
| SCHEMBL8395954 | 0.87 | HIF1A (0.41) | HIF1ASMN1; SMN2L3MBTL1KMT2AGAA | |
| SCHEMBL8397983 | 0.87 | TDP1 (0.41) | HIF1ASMN1; SMN2L3MBTL1KDM4EMAPT | |
| SCHEMBL8395436 | 0.85 | MCL1 (0.45) | HIF1AKDM4EMAOBALDH1A1 | |
| SCHEMBL896797 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL8397935 | 0.84 | MRGPRX4 (0.41) | HIF1ASMN1; SMN2L3MBTL1MAPTLMNA | |
| SCHEMBL7646069 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL8399059 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |