Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395326 | 0.91 | LMNA (0.43) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL8399054 | 0.88 | MEN1 (0.43) | KMT2AMEN1ALDH1A1POLBHPGD | |
| SCHEMBL8399075 | 0.85 | KMT2A (0.42) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL8396067 | 0.85 | NISCH (0.38) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL8399231 | 0.84 | HIF1A (0.44) | KMT2AMEN1DCPSHIF1A | |
| SCHEMBL8396050 | 0.84 | RECQL (0.44) | KMT2AALDH1A1KDM4EL3MBTL1MAPT | |
| SCHEMBL8396086 | 0.83 | TP53 (0.47) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL8400215 | 0.82 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL8397935 | 0.82 | MRGPRX4 (0.41) | POLBHPGDLMNAL3MBTL1MAPK1 | |
| SCHEMBL8396125 | 0.82 | RXRA (0.42) | LMNASMN1; SMN2ATMHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |