Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.85 |
| ▸ | MMP2 | P08253 | 6/20 | 0.85 |
| ▸ | MMP8 | P22894 | 5/20 | 0.85 |
| ▸ | MMP9 | P14780 | 3/20 | 0.73 |
| ▸ | MMP7 | P09237 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016080 | 0.92 | MMP1 (0.86) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL3789890 | 0.92 | MMP1 (0.86) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL13059991 | 0.92 | MMP1 (0.86) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL3794318 | 0.87 | MMP8 (0.80) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL6013895 | 0.87 | MMP8 (0.80) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL6016085 | 0.87 | MMP8 (0.80) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL7457278 | 0.87 | MMP1 (0.78) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL6575485 | 0.86 | MMP1 (0.82) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL7412775 | 0.86 | MMP2 (0.84) | MMP1MMP2MMP8MMP9MMP7 | |
| SCHEMBL6577793 | 0.84 | MMP2 (1.00) | MMP1MMP2MMP8MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892112-A | ACYLATION OF AMINO ACIDS WITH ANHYDRIDES OR CARBOXY GROUPS, AMIDATION WITH AMINE AND CONVERSION OF ACID OR ESTER TO HYDROXAMIC ACID AND HYDROLYSIS | GLYCOMED INCORPORATED (US) | 1999-04-06 | — | — | US | disclosed |