Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 8/20 | 0.80 |
| ▸ | MMP9 | P14780 | 6/20 | 0.80 |
| ▸ | MMP1 | P03956 | 9/20 | 0.78 |
| ▸ | MMP2 | P08253 | 8/20 | 0.78 |
| ▸ | NMBR | P28336 | 2/20 | 0.67 |
| ▸ | MMP7 | P09237 | 1/20 | 0.66 |
| ▸ | BMP1 | P13497 | 1/20 | 0.64 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013895 | 1.00 | MMP8 (0.80) | MMP8MMP9MMP1MMP2NMBR | |
| SCHEMBL3794318 | 1.00 | MMP8 (0.80) | MMP8MMP9MMP1MMP2NMBR | |
| SCHEMBL6431245 | 0.92 | MMP8 (0.75) | MMP8MMP9MMP1MMP2NMBR | |
| SCHEMBL3798651 | 0.91 | MMP8 (0.74) | MMP8MMP9MMP1MMP2NMBR | |
| SCHEMBL8396457 | 0.87 | MMP1 (0.85) | MMP8MMP9MMP1MMP2MMP7 | |
| SCHEMBL7457278 | 0.86 | MMP1 (0.78) | MMP8MMP9MMP1MMP2NMBR | |
| SCHEMBL7412775 | 0.85 | MMP2 (0.84) | MMP8MMP9MMP1MMP2MMP7 | |
| SCHEMBL3798655 | 0.85 | MMP1 (0.74) | MMP8MMP9MMP1MMP2MMP7 | |
| SCHEMBL2421029 | 0.85 | NMBR (0.85) | NMBRBMP1SIRT5 | |
| SCHEMBL2370248 | 0.85 | NMBR (0.85) | NMBRBMP1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060239926-A1 | Specific high-relaxivity compounds | GUERBET (FR) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060239926-A1 | Specific high-relaxivity compounds | TNNC1, TNNT2, TNNI3 | MMP8 2023/4885MMP9 888/4885MMP1 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.