Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400210 | 0.94 | THRA (0.41) | PPARDHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL8397742 | 0.93 | THRA (0.46) | PPARDABCB1LTB4RLTB4R2THRA | |
| SCHEMBL8396067 | 0.92 | NISCH (0.38) | NISCHHIF1AALDH1A1SLC1A5SNCA | |
| SCHEMBL8396234 | 0.88 | PPARD (0.39) | PPARDHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL8396050 | 0.86 | RECQL (0.44) | ALDH1A1SLC1A5 | |
| SCHEMBL8396086 | 0.85 | TP53 (0.47) | ALDH1A1SLC1A5 | |
| SCHEMBL8395326 | 0.85 | LMNA (0.43) | THRBALDH1A1SLC1A5 | |
| SCHEMBL8400227 | 0.83 | NISCH (0.37) | NISCHHIF1AALDH1A1SLC1A5SLC6A2 | |
| SCHEMBL8398841 | 0.83 | L3MBTL1 (0.42) | ALDH1A1SLC1A5 | |
| SCHEMBL8396125 | 0.83 | RXRA (0.42) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |