Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399168 | 0.89 | L3MBTL1 (0.38) | GSK3BERBB2KDM4EALDH1A1HTT | |
| SCHEMBL8399102 | 0.86 | MEN1 (0.36) | GSK3BERBB2KDM4ETRPM5MAPT | |
| SCHEMBL8398164 | 0.86 | ADRA2C (0.40) | GSK3BERBB2ALDH1A1HTTNAAA | |
| SCHEMBL8397939 | 0.84 | ADRA1D (0.40) | GSK3BKDM4EALDH1A1NAAAAKR1B1 | |
| SCHEMBL8395190 | 0.83 | L3MBTL1 (0.44) | GSK3BERBB2ALDH1A1HTTRAB9A | |
| SCHEMBL8399066 | 0.82 | CYP1A2 (0.35) | KDM4EALDH1A1NAAAAKR1B1RAB9A | |
| SCHEMBL8395348 | 0.81 | AKR1B1 (0.39) | ERBB2KDM4EALDH1A1HTTAKR1B1 | |
| SCHEMBL8396103 | 0.81 | AKR1B1 (0.41) | GSK3BERBB2KDM4EALDH1A1HTT | |
| SCHEMBL8396660 | 0.80 | MEN1 (0.36) | ERBB2ALDH1A1HTTTRPM5RAB9A | |
| SCHEMBL8395427 | 0.79 | EGFR (0.38) | ERBB2MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |