Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 9/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395524 | 0.90 | AKR1B1 (0.43) | AKR1B1HTTGSK3BKDM4EALDH1A1 | |
| SCHEMBL8396268 | 0.86 | AKR1B1 (0.41) | AKR1B1HTTALDH1A1MAPTNPC1 | |
| SCHEMBL8395800 | 0.86 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL8399286 | 0.84 | AKR1B1 (0.39) | AKR1B1KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8399103 | 0.83 | L3MBTL1 (0.43) | AKR1B1HTTKDM4EALDH1A1MAPT | |
| SCHEMBL8399351 | 0.83 | AKR1B1 (0.46) | AKR1B1MAPTNPC1RAB9A | |
| SCHEMBL8395435 | 0.81 | AKR1B1 (0.38) | AKR1B1HTTALDH1A1MAPTNPC1 | |
| SCHEMBL8399083 | 0.81 | GSK3B (0.34) | AKR1B1HTTGSK3BERBB2KDM4E | |
| SCHEMBL8399092 | 0.80 | AKR1B1 (0.38) | AKR1B1ERBB2 | |
| SCHEMBL8398073 | 0.80 | AKR1B1 (0.45) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |