Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396429 | 0.91 | LTB4R2 (0.33) | LTB4R2AKR1B1 | |
| SCHEMBL8396430 | 0.90 | SMN1; SMN2 (0.39) | LTB4R2 | |
| SCHEMBL8982219 | 0.89 | STK17B (0.32) | STK17BAKR1B1MAP3K8STK17A | |
| SCHEMBL8398137 | 0.88 | RAB9A (0.40) | LTB4R2AKR1B1 | |
| SCHEMBL8399085 | 0.88 | LTB4R2 (0.40) | LTB4R2 | |
| SCHEMBL8398694 | 0.87 | AKR1B1 (0.40) | STK17BLTB4R2AKR1B1GAA | |
| SCHEMBL8399483 | 0.87 | HDAC6 (0.39) | LTB4R2 | |
| SCHEMBL8395274 | 0.86 | AKR1B1 (0.37) | AKR1B1GAAHPGD | |
| SCHEMBL8399115 | 0.86 | MTNR1A (0.40) | LTB4R2 | |
| SCHEMBL8396071 | 0.86 | LTB4R2 (0.36) | LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |