Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13138487 | 0.82 | SIGMAR1 (0.50) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL4982326 | 0.77 | SIGMAR1 (0.90) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL8399385 | 0.74 | SIGMAR1 (0.61) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL4981507 | 0.68 | SIGMAR1 (0.73) | SIGMAR1 | |
| SCHEMBL8399382 | 0.67 | KMT2A (0.48) | SIGMAR1CYP2D6 | |
| SCHEMBL17968404 | 0.67 | SIGMAR1 (0.61) | SIGMAR1CYP2D6 | |
| SCHEMBL27844570 | 0.66 | SIGMAR1 (0.56) | SIGMAR1CYP2D6 | |
| SCHEMBL8742588 | 0.66 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL6541295 | 0.65 | SIGMAR1 (0.46) | SIGMAR1TP53TSHR | |
| SCHEMBL8152318 | 0.65 | MCL1 (0.58) | SIGMAR1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790912-B2 | Devices containing chiroptical switching materials and methods of making and using the same | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090148673-A1 | DEVICES CONTAINING CHIROPTICAL SWITCHING MATERIALS AND METHODS OF MAKING AND USING THE SAME | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-11 | — | — | US | disclosed |
| US-7485740-B2 | Devices containing chiroptical switching materials and methods of making and using the same | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-02-03 | — | — | US | disclosed |
| US-20070170422-A1 | Devices containing chiroptical switching materials and methods of making and using the same | NORTH CAROLINA STATE UNIVERSITY | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070170422-A1 | Devices containing chiroptical switching materials and methods of making and using the same | PLEC, NCS1, PIEZO1 | SIGMAR1 4565/4885TP53 4314/4885CYP2D6 4825/4885 |
| US-20090148673-A1 | DEVICES CONTAINING CHIROPTICAL SWITCHING MATERIALS AND METHODS OF MAKING AND USING THE SAME | PLEC, NCS1, PIEZO1 | SIGMAR1 4565/4885TP53 4314/4885CYP2D6 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.