Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468700 | 0.65 | ALDH1A1 (0.43) | KDM4EALDH1A1GAA | |
| SCHEMBL1351954 | 0.65 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL8399400 | 0.64 | MAPK1 (0.33) | MAPTMAPK1EPHX2 | |
| SCHEMBL6247351 | 0.64 | OXTR (0.53) | KDM4EOXTRAVPR1AMAPTMAPK1 | |
| SCHEMBL8399397 | 0.63 | EPHX2 (0.44) | KDM4ELMNAALDH1A1GAAMAPT | |
| SCHEMBL9690349 | 0.62 | CCKBR (0.52) | CCKBR | |
| SCHEMBL4798163 | 0.61 | EPHX2 (0.53) | GAAEPHX2 | |
| SCHEMBL4798177 | 0.61 | EPHX2 (0.53) | GAAEPHX2 | |
| SCHEMBL17916932 | 0.61 | EPHX2 (0.53) | GAAEPHX2 | |
| SCHEMBL30885132 | 0.61 | MAPK1 (0.49) | MAPK1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |