Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137796 | 0.89 | — | — | |
| SCHEMBL8122960 | 0.88 | CXCR2 (0.30) | MAPTHPGDTSHRTAAR1HSD17B10 | |
| SCHEMBL6725582 | 0.81 | RXRA (0.34) | HPGDHSD17B10 | |
| SCHEMBL8351478 | 0.77 | ABCC1 (0.34) | — | |
| SCHEMBL8346248 | 0.75 | HPGD (0.33) | MAPTHPGDTSHRTAAR1HSD17B10 | |
| SCHEMBL8399488 | 0.75 | MAPT (0.46) | MAPTHPGDTSHRTAAR1HSD17B10 | |
| SCHEMBL6723893 | 0.72 | KDM4E (0.33) | MAPTHPGDHSD17B10 | |
| SCHEMBL6721354 | 0.72 | RXRA (0.33) | HPGDHSD17B10 | |
| SCHEMBL8137795 | 0.71 | — | — | |
| SCHEMBL6725367 | 0.69 | RXRA (0.35) | MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885936-A | BENZOTHIOPYRAN DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0860441-A1 | Herbicidal derivatives of 1,4-dithiino(2,3c)benzothiopyran | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-26 | — | — | EP | disclosed |