Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 8/20 | 0.33 |
| ▸ | RXRG | P48443 | 5/20 | 0.33 |
| ▸ | RXRB | P28702 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725582 | 0.85 | RXRA (0.34) | KDM4EMEN1KMT2AABCC1TDP1 | |
| SCHEMBL8122242 | 0.81 | RXRA (0.33) | KDM4EMEN1KMT2AABCC1TDP1 | |
| SCHEMBL8137314 | 0.74 | CYP3A4 (0.33) | KDM4EABCC1RXRARXRGRXRB | |
| SCHEMBL6732599 | 0.73 | SMN1; SMN2 (0.35) | MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6721354 | 0.72 | RXRA (0.33) | KDM4EMEN1KMT2AABCC1RXRA | |
| SCHEMBL6725367 | 0.72 | RXRA (0.35) | KDM4EMEN1KMT2ATDP1RXRA | |
| SCHEMBL8351478 | 0.72 | ABCC1 (0.34) | ABCC1RXRARXRGRXRB | |
| SCHEMBL8399431 | 0.72 | MAPT (0.31) | HPGDHSD17B10MAPT | |
| SCHEMBL8120542 | 0.70 | SPR (0.32) | — | |
| SCHEMBL6772501 | 0.69 | KDM4E (0.35) | KDM4EMEN1KMT2AABCC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677460-B1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| EP-0810226-B1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN CO (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2002-09-19 | — | — | US | disclosed |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6136755-A | HERBICIDES | IDEMITSU KOSAN CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6103668-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-08-15 | — | — | US | disclosed |
| US-6063936-A | CARBOXY SUBSTITUTED BENZOTHIOPHENES USED AS HERBICIDE | IDEMITSU KOSAN CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5767289-A | HERBICIDE INTERMEDIATES | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0810226-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5607898-A | HERBICIDES | IDEMITSU KOSAN COMPANY, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236421-A1 | AROMATIC CARBOXYLIC ACID BICYCLIC SULFUR COMPOUNDS | XDH, SULT2A1, NAT1 | KDM4E 3095/4885MEN1 4319/4885KMT2A 2204/4885 |
| US-20010051733-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | KDM4E 3095/4885MEN1 4319/4885KMT2A 2204/4885 |
| US-20020133024-A1 | Aromatic carboxylic acid bicyclic sulfur compounds | XDH, SULT2A1, NAT1 | KDM4E 3095/4885MEN1 4319/4885KMT2A 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.