Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MAP2 | P11137 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784721 | 0.84 | POLB (0.48) | CA1CA2ADORA3KDM4ETNKS | |
| SCHEMBL8401455 | 0.83 | LMNA (0.47) | CA1CA2ADORA3KDM4EL3MBTL1 | |
| SCHEMBL8784504 | 0.83 | KDM4E (0.56) | CA1CA2ADORA3KDM4ETNKS | |
| SCHEMBL8403474 | 0.80 | LMNA (0.42) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11626175 | 0.80 | CA1 (0.55) | CA1CA2ADORA3KDM4EL3MBTL1 | |
| SCHEMBL8402613 | 0.79 | SMN1; SMN2 (0.45) | CA1CA2ADORA3KDM4EL3MBTL1 | |
| SCHEMBL11545978 | 0.78 | MCL1 (0.61) | KDM4EALDH1A1HPGDHSD17B10MCL1 | |
| SCHEMBL8401426 | 0.78 | MCL1 (0.61) | CA1CA2ADORA3KDM4ETNKS | |
| SCHEMBL28837168 | 0.78 | CA1 (0.49) | CA1CA2ADORA3KDM4EL3MBTL1 | |
| SCHEMBL25824715 | 0.77 | ADORA3 (0.65) | CA1CA2ADORA3KDM4ETNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929107-A | INHIBITORS OF ACYL-COA:CHOLESTEROL ACYLTRANSFERASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5492929-A | ENZYME INHIBITORS, ANTICHOLESTEROL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-20 | — | — | US | disclosed |
| EP-0602598-A1 | 3-Phenylindolyl-, -benzofuranyl- and -benzothienyl- alkylcarboxanilides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-06-22 | — | — | EP | disclosed |