Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402756 | 0.80 | ALDH1A1 (0.55) | POLBLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8403511 | 0.79 | L3MBTL1 (0.58) | LMNAMEN1KMT2A | |
| SCHEMBL6753728 | 0.71 | POLB (0.62) | POLBRAB9ALMNABTKMEN1 | |
| SCHEMBL19409427 | 0.70 | POLB (0.64) | POLBRAB9ABTKMEN1KMT2A | |
| SCHEMBL29436997 | 0.70 | POLB (0.64) | POLBRAB9ABTKMEN1KMT2A | |
| SCHEMBL31540604 | 0.69 | MEN1 (0.56) | POLBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL29965729 | 0.69 | MEN1 (0.56) | POLBRAB9ABTKMEN1KMT2A | |
| SCHEMBL122995 | 0.69 | MEN1 (0.56) | POLBRAB9ABTKMEN1KMT2A | |
| SCHEMBL16586798 | 0.69 | POLB (0.67) | POLBRAB9ALMNAMEN1KMT2A | |
| SCHEMBL15653014 | 0.68 | BTK (0.53) | POLBBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885997-A | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-23 | — | — | US | disclosed |