Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402756 | 0.90 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1KMT2AMEN1HRH3 | |
| SCHEMBL8399369 | 0.82 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1HIF1AKMT2AMEN1 | |
| SCHEMBL8401465 | 0.81 | ALDH1A1 (0.76) | L3MBTL1ALDH1A1HIF1AKMT2AMEN1 | |
| SCHEMBL4465299 | 0.80 | L3MBTL1 (0.79) | L3MBTL1ALDH1A1HIF1ALMNA | |
| SCHEMBL8401523 | 0.79 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8399473 | 0.79 | POLB (0.48) | KMT2AMEN1LMNA | |
| SCHEMBL8399433 | 0.79 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11435540 | 0.76 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1KMT2AMEN1PDE10A | |
| SCHEMBL8402601 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HIF1AKMT2ACYP1A2CYP3A4 | |
| SCHEMBL8399521 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885997-A | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-23 | — | — | US | disclosed |