Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442483 | 0.82 | ESR1 (0.39) | TRPA1ALDH1A1ESR1ESR2ADRB2 | |
| SCHEMBL842106 | 0.81 | ESR1 (0.36) | TSHRESR1ESR2MAPK1ATM | |
| SCHEMBL927038 | 0.76 | IDO1 (0.33) | TSHRTRPA1ALDH1A1ESR1ESR2 | |
| SCHEMBL5490776 | 0.76 | CYP1A2 (0.42) | ALDH1A1MAPK1 | |
| SCHEMBL190146 | 0.75 | IDO1 (0.52) | TSHRTRPA1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL7550160 | 0.75 | ESR1 (0.46) | TSHRTRPA1ALDH1A1ESR1ESR2 | |
| SCHEMBL927598 | 0.73 | IDO1 (0.32) | TSHRTRPA1ALDH1A1ESR1ESR2 | |
| SCHEMBL839864 | 0.73 | CHRNA7 (0.41) | TRPA1ALDH1A1ESR1ESR2TDP1 | |
| SCHEMBL5484844 | 0.73 | ADRB2 (0.52) | TSHRMAPK1TDP1ADRB2LMNA | |
| SCHEMBL17816125 | 0.71 | TSHR (0.40) | TSHRTRPA1ALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310446-B1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-8143336-B2 | Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-27 | — | — | US | disclosed |
| EP-2310446-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | Momentive Performance Materials Inc. (US) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010017370-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20100036018-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-02-11 | — | — | US | disclosed |