Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442483 | 0.87 | ESR1 (0.39) | ALDH1A1 | |
| SCHEMBL839864 | 0.78 | CHRNA7 (0.41) | ALOX5ALDH1A1CYP19A1SMN1; SMN2 | |
| SCHEMBL5484844 | 0.78 | ADRB2 (0.52) | CYP2A6MAPK1CYP19A1HPGD | |
| SCHEMBL9854662 | 0.78 | CYP2A6 (0.40) | CYP1A2CYP2A6ALOX5PYCR1ALDH1A1 | |
| SCHEMBL839956 | 0.76 | TSHR (0.36) | ALDH1A1MAPK1 | |
| SCHEMBL208902 | 0.75 | TSHR (0.43) | ALDH1A1KDM4E | |
| SCHEMBL7795647 | 0.75 | TSHR (0.43) | ALDH1A1KDM4E | |
| SCHEMBL9644426 | 0.73 | CYP3A4 (0.44) | ALDH1A1MAPK1CYP19A1SMN1; SMN2 | |
| SCHEMBL2727066 | 0.73 | LMNA (0.44) | ALDH1A1ALOX15HPGD | |
| SCHEMBL5484876 | 0.73 | ALDH1A1 (0.50) | CYP1A2ALDH1A1MAPK1CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-0731105-B1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-0731105-A1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-09-11 | — | — | EP | disclosed |