Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442483 | 0.89 | ESR1 (0.39) | ALDH1A1GAAESR1PDCD1ESR2 | |
| Toluene SCHEMBL18394200 | 0.84 | LMNA (0.48) | ACHELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5484844 | 0.80 | ADRB2 (0.52) | TDP1CYP19A1LMNASLC6A2ADRB2 | |
| SCHEMBL5490776 | 0.78 | CYP1A2 (0.42) | CYP19A1ALOX5ALDH1A1SMN1; SMN2 | |
| SCHEMBL12853319 | 0.77 | CHRNA7 (0.42) | CHRNA7ACHETDP1CYP19A1ALOX5 | |
| SCHEMBL7795647 | 0.77 | TSHR (0.43) | ALDH1A1TRPA1LMNA | |
| SCHEMBL208902 | 0.77 | TSHR (0.43) | ALDH1A1TRPA1LMNA | |
| SCHEMBL9644426 | 0.75 | CYP3A4 (0.44) | CYP19A1ALDH1A1GAALMNACHRM1 | |
| SCHEMBL5484876 | 0.75 | ALDH1A1 (0.50) | ACHETDP1CYP19A1ALDH1A1GAA | |
| SCHEMBL2727066 | 0.75 | LMNA (0.44) | TDP1ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310446-B1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-23 | — | — | EP | disclosed |
| CN-102432924-B | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2014-04-09 | — | — | CN | disclosed |
| CN-102177197-B | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2013-11-06 | — | — | CN | disclosed |
| CN-101641226-B | Rubber composition, method of making the same, and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2013-02-13 | — | — | CN | disclosed |
| CN-102432924-A | Rubber composition, method of making the same, and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2012-05-02 | — | — | CN | disclosed |
| US-8143336-B2 | Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-27 | — | — | US | disclosed |
| CN-102177197-A | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2011-09-07 | — | — | CN | disclosed |
| EP-2310446-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | Momentive Performance Materials Inc. (US) | 2011-04-20 | — | — | EP | disclosed |
| EP-2121349-B1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2010-11-17 | — | — | EP | disclosed |
| US-20100036018-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-02-11 | — | — | US | disclosed |
| CN-101641226-A | Rubber composition, method of making the same, and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2010-02-03 | — | — | CN | disclosed |
| US-7625965-B2 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-12-01 | — | — | US | disclosed |
| EP-2121349-A1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008097587-A1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC (US) | 2008-08-14 | — | — | WO | disclosed |
| US-20080194746-A1 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-08-14 | — | — | US | disclosed |
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-20040082803-A1 | Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2004-04-29 | — | — | US | disclosed |
| EP-0731105-B1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-0731105-A1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082803-A1 | Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane | CBR1, OXSR1, HCCS | CHRNA7 1590/4885ACHE 4320/4885TDP1 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.