Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 5/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 3/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092638 | 0.81 | HNF4A (0.50) | FABP5FABP7L3MBTL1FABP3KMT2A | |
| SCHEMBL27583741 | 0.76 | KEAP1 (0.49) | FABP5FABP7KMT2AKDM4EALDH1A1 | |
| SCHEMBL246689 | 0.73 | HNF4A (0.46) | FABP5TOP1FABP7TDP1L3MBTL1 | |
| SCHEMBL4624902 | 0.72 | ALDH1A1 (0.39) | FABP5FABP7L3MBTL1KMT2AKDM4E | |
| Acetic Acid SCHEMBL28553657 | 0.72 | POLB (0.48) | FABP5FABP7KMT2AHRH3 | |
| SCHEMBL27961252 | 0.72 | TOP1 (0.46) | TOP1TDP1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3062707 | 0.72 | HTR2A (0.47) | FABP5FABP7KMT2AHRH3 | |
| SCHEMBL1639323 | 0.71 | FABP3 (0.56) | FABP5FABP7TDP1L3MBTL1FABP3 | |
| SCHEMBL30563023 | 0.71 | FABP3 (0.56) | FABP5FABP7TDP1L3MBTL1FABP3 | |
| SCHEMBL9449421 | 0.71 | HTR2A (0.42) | KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672700-B1 | PNA-synthesis using an aminoprotecting group which is labile against weak acids | HOECHST AG (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0672700-A1 | PNA-synthesis using an aminoprotecting group which is labile against weak acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |