Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400228 | 0.92 | LTB4R2 (0.35) | AKR1B1TP53LTB4R2MAPT | |
| SCHEMBL8399344 | 0.91 | HDAC6 (0.37) | AKR1B1TP53LTB4R2CNR2 | |
| SCHEMBL8395274 | 0.90 | AKR1B1 (0.37) | AKR1B1TP53SMN1; SMN2 | |
| SCHEMBL8399247 | 0.90 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL8399251 | 0.89 | TSHR (0.40) | AKR1B1TP53LTB4R2MAPT | |
| SCHEMBL8400120 | 0.89 | LTB4R2 (0.37) | AKR1B1TP53LTB4R2 | |
| SCHEMBL8399615 | 0.89 | USP5 (0.35) | AKR1B1TP53SMN1; SMN2KMT2A | |
| SCHEMBL8399176 | 0.89 | SMN1; SMN2 (0.44) | TP53CNR2CNR1SMN1; SMN2MAPT | |
| SCHEMBL8982219 | 0.89 | STK17B (0.32) | AKR1B1 | |
| SCHEMBL8398137 | 0.88 | RAB9A (0.40) | AKR1B1TP53LTB4R2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |