Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | RNF4 | P78317 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399271 | 0.90 | SMN1; SMN2 (0.39) | TSHRUSP2TP53HDAC1LMNA | |
| SCHEMBL8399115 | 0.90 | MTNR1A (0.40) | LMNALTB4R2NPC1RAB9APTGDR2 | |
| SCHEMBL8399708 | 0.89 | AKR1B1 (0.35) | TP53LTB4R2MAPTAKR1B1 | |
| SCHEMBL8400228 | 0.89 | LTB4R2 (0.35) | TSHRTP53LMNAALDH1A1LTB4R2 | |
| SCHEMBL8399348 | 0.89 | LTB4R2 (0.39) | TP53LMNAALDH1A1LTB4R2MAPT | |
| SCHEMBL8399344 | 0.88 | HDAC6 (0.37) | TP53LTB4R2AKR1A1AKR1B1 | |
| SCHEMBL8395274 | 0.88 | AKR1B1 (0.37) | TSHRTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL8399247 | 0.87 | AKR1B1 (0.32) | PTGDR2AKR1A1AKR1B1 | |
| SCHEMBL8982219 | 0.86 | STK17B (0.32) | AKR1B1 | |
| SCHEMBL8400120 | 0.86 | LTB4R2 (0.37) | TP53LTB4R2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |