SCHEMBL8400097

SCHEMBL8400097

Cc1ccc2ncnnc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.43
ALDH1A1 P00352 3/20 0.39
CYP1A2 P05177 2/20 0.39
KDM4E B2RXH2 4/20 0.38
HTT P42858 3/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
KMT2A Q03164 1/20 0.35
NCK1 P16333 1/20 0.35
BACE1 P56817 1/20 0.35
PARP1 P09874 2/20 0.35
CHEK1 O14757 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6028972 0.91 NQO2 (0.43) NQO2ALDH1A1CYP1A2KDM4EHTT
SCHEMBL8400256 0.75 SCN10A (0.38) ALDH1A1L3MBTL1MAPTTDP1LMNA
SCHEMBL8401811 0.74 PIK3CG (0.47) ALDH1A1CYP1A2KDM4EHTTMAPT
SCHEMBL8208335 0.74 EGFR (0.47) ALDH1A1KDM4EHTTMAPTLMNA
SCHEMBL21477557 0.74 NPC1 (0.42) ALDH1A1KDM4EHTTL3MBTL1MAPT
SCHEMBL18609103 0.72 NQO2 (0.50) NQO2ALDH1A1CYP1A2KDM4EHTT
SCHEMBL30178501 0.72 ALDH1A1 (0.56) NQO2ALDH1A1CYP1A2KDM4EL3MBTL1
SCHEMBL27449 0.72 ALDH1A1 (0.56) NQO2ALDH1A1CYP1A2KDM4EL3MBTL1
SCHEMBL88615 0.69 EGFR (0.41) ALDH1A1KDM4EHTTMAPTTDP1
SCHEMBL29599774 0.69 EGFR (0.41) ALDH1A1KDM4EHTTMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751475-B2 Organic compound, display panel and display apparatus XIAMEN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-09-05 US disclosed
WO-2023275337-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2023-01-05 WO disclosed
WO-2023275336-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2023-01-05 WO disclosed
WO-2023275333-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2023-01-05 WO disclosed
WO-2021058592-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-04-01 WO disclosed
EP-3556750-B1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME LG CHEMICAL LTD (KR) 2021-02-24 EP disclosed
EP-3556750-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME LG Chem, Ltd. (KR) 2019-10-23 EP disclosed
WO-2017040993-A1 SMALL MOLECULE INHIBITORS OF DYRK1A AND USES THEREOF THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-03-09 WO disclosed
US-5856325-A REDUCING INFLAMMATION BY INHIBITING PLA2 IN A MAMMAL BOEHRINGER MANNHEIM GMBH (DE) 1999-01-05 US disclosed
EP-0259371-B1 PREPARATION OF 3-DIMETHYLAMINO-7-METHYL-1,2,4-BENZOTRIAZINE-1-OXIDE AND AZAPROPAZONE JOHN WYETH & BROTHER LIMITED (GB) 1992-05-13 EP disclosed
EP-0259371-A1 PREPARATION OF 3-DIMETHYLAMINO-7-METHYL-1,2,4-BENZOTRIAZINE-1-OXIDE AND AZAPROPAZONE. ROBINS A H CO LTD (GB) 1988-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11751475-B2 Organic compound, display panel and display apparatus C3AR1, NR0B2, NR0B1 NQO2 3819/4885ALDH1A1 1591/4885CYP1A2 957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.