SCHEMBL8400339

SCHEMBL8400339

c1ccc(-c2nc(-c3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)cc(-c3ccccn3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
MAPT P10636 5/20 0.42
MEN1 O00255 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 3/20 0.42
NTSR1 P30989 1/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
DHODH Q02127 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PPP1CA P62136 1/20 0.41
RAB9A P51151 3/20 0.40
LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19271517 1.00 KMT2A (0.42) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL15394838 0.99 KMT2A (0.43) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL8400351 0.99 KMT2A (0.43) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL17853560 0.96 DHODH (0.45) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL17853563 0.96 DHODH (0.45) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL17853502 0.96 DHODH (0.45) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL17853545 0.96 DHODH (0.45) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL9968547 0.95 METAP1 (0.40) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL17853487 0.95 DHODH (0.46) KMT2AMAPTMEN1ALDH1A1HPGD
SCHEMBL12579405 0.95 DHODH (0.46) KMT2AMAPTMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389110-B1 ORGANIC ELECTROLUMINESCENT ELEMENT UDC IRELAND LTD (IE) 2023-12-27 EP disclosed
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
US-10651398-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-05-12 US disclosed
US-10431749-B2 Organic electroluminescent element UDC IRELAND LIMITED (IE) 2019-10-01 US disclosed
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-01-29 US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 US disclosed
US-20170229660-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed
US-20170229660-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed
US-9530969-B2 Material for organic electroluminescence device and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-12-27 US disclosed
US-9530969-B2 Material for organic electroluminescence device and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-12-27 US disclosed
US-20120126692-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126691-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
WO-2011013859-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-02-03 WO disclosed
EP-2169028-A2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same Idemitsu Kosan Co., Ltd. (JP) 2010-03-31 EP disclosed
US-20070257600-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-08 US disclosed
US-20070257600-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 KMT2A 2781/4885MAPT 716/4885MEN1 260/4885
US-10431749-B2 Organic electroluminescent element EML4, L1CAM, EPHA4 KMT2A 2388/4885MAPT 2678/4885MEN1 1717/4885
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L KMT2A 2152/4885MAPT 3476/4885MEN1 1270/4885
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same UQCRB, OXA1L, HBS1L KMT2A 2201/4885MAPT 3383/4885MEN1 1397/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 KMT2A 2781/4885MAPT 716/4885MEN1 260/4885
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same UQCRB, OXA1L, HBS1L KMT2A 2201/4885MAPT 3383/4885MEN1 1397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.