SCHEMBL8400398

SCHEMBL8400398

c1ccc(-c2cc(-c3cccc(-c4cc(-c5ccccc5)nc(-c5cccc(-n6c7ccccc7c7ccccc76)c5)c4)c3)cc(-c3cccc(-n4c5ccccc5c5ccccc54)c3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ATM Q13315 1/20 0.49
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.37
ACHE P22303 1/20 0.37
CYP19A1 P11511 1/20 0.37
HPGD P15428 3/20 0.36
LMNA P02545 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
PDE10A Q9Y233 2/20 0.36
IL1R1 P14778 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17539753 1.00 KDM4E (0.49) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL17539736 1.00 KDM4E (0.49) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL14425637 0.99 ATM (0.47) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL14425633 0.99 ATM (0.47) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL14425643 0.98 L3MBTL1 (0.50) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL8739848 0.98 KDM4E (0.50) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL17539748 0.97 ATM (0.46) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL17539752 0.97 ATM (0.46) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL17539756 0.97 ATM (0.46) KDM4EL3MBTL1ATMGABRG2GABRB3
SCHEMBL17539745 0.97 ATM (0.46) KDM4EL3MBTL1ATMGABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389110-B1 ORGANIC ELECTROLUMINESCENT ELEMENT UDC IRELAND LTD (IE) 2023-12-27 EP disclosed
US-10431749-B2 Organic electroluminescent element UDC IRELAND LIMITED (IE) 2019-10-01 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-20130292654-A1 Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2013-11-07 US disclosed
US-20130292654-A1 Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2013-11-07 US disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed
US-20120126691-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126691-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126692-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126692-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-7777043-B2 Compound, charge transporting material and organic electroluminescent element MITSUBISHI CHEMICAL CORPORATION (JP) 2010-08-17 US disclosed
US-7777043-B2 Compound, charge transporting material and organic electroluminescent element MITSUBISHI CHEMICAL CORPORATION (JP) 2010-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE SLC26A3, SLC43A3, SLCO2A1 KDM4E 4092/4885L3MBTL1 1106/4885ATM 3592/4885
US-10431749-B2 Organic electroluminescent element EML4, L1CAM, EPHA4 KDM4E 427/4885L3MBTL1 156/4885ATM 2840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.