Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396813 | 0.81 | ALPL (0.46) | ALPLALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8400102 | 0.78 | CA12 (0.46) | ALPLALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8519653 | 0.78 | CA12 (0.46) | ALPLALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL30704314 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDPTGS2KDM4E | |
| SCHEMBL2405190 | 0.75 | KDM4E (0.53) | ALPLCA9PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL899644 | 0.75 | BACE1 (0.52) | ALDH1A1MAPTHPGDRECQLPTGS2 | |
| SCHEMBL30529887 | 0.74 | ALDH1A1 (0.51) | ALPLCA9PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL8401146 | 0.74 | MAPK1 (0.45) | PTGDR2 | |
| SCHEMBL10982371 | 0.74 | ALDH1A1 (0.50) | CA9ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL10984490 | 0.73 | ALDH1A1 (0.46) | CA9ALDH1A1MAPTHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948916-A | Arylthiadiazole derivative and antiviral agent containing the same | RATIONAL DRUG DESIGN LABORATORIES (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0785193-A1 | ARYLTHIADIAZOLE DERIVATIVE AND ANTIVIRAL AGENT CONTAINING THE SAME | Rational Drug Design Laboratories (JP) | 1997-07-23 | — | — | EP | disclosed |