Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338995 | 0.83 | KDM4E (0.52) | MAPK1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL8519653 | 0.82 | CA12 (0.46) | CA12ALPLPTGDR2MAP2K4ALDH1A1 | |
| SCHEMBL8396813 | 0.82 | ALPL (0.46) | ALPLMAPK1MAP2K4MAPK6ALDH1A1 | |
| SCHEMBL8401146 | 0.81 | MAPK1 (0.45) | PTGDR2MAPK1MAP2K4MAPK6 | |
| SCHEMBL8397343 | 0.80 | PIN1 (0.50) | PTGDR2MAP2K4KDM4E | |
| SCHEMBL8400437 | 0.78 | ALPL (0.50) | ALPLPTGDR2ALDH1A1KDM4EMAPT | |
| SCHEMBL27081216 | 0.78 | RAB9A (0.41) | MAPK1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL30704329 | 0.73 | ALOX5 (0.39) | BCL2L1BADPTGDR2MAPK1ALDH1A1 | |
| SCHEMBL1966662 | 0.73 | BCL2L1 (0.47) | CA12ALPLRPA1BCL2L1BAD | |
| SCHEMBL8400098 | 0.70 | PIN1 (0.52) | ALDH1A1KDM4ENPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948916-A | Arylthiadiazole derivative and antiviral agent containing the same | RATIONAL DRUG DESIGN LABORATORIES (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0785193-A1 | ARYLTHIADIAZOLE DERIVATIVE AND ANTIVIRAL AGENT CONTAINING THE SAME | Rational Drug Design Laboratories (JP) | 1997-07-23 | — | — | EP | disclosed |