Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.45 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.45 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400098 | 0.82 | PIN1 (0.52) | SRD5A2 | |
| SCHEMBL8400102 | 0.81 | CA12 (0.46) | MAPK1MAP2K4MAPK6PTGDR2 | |
| SCHEMBL10338995 | 0.79 | KDM4E (0.52) | MAPK1DHODH | |
| SCHEMBL8519653 | 0.78 | CA12 (0.46) | MAP2K4DHODHPTGDR2 | |
| SCHEMBL8396813 | 0.78 | ALPL (0.46) | MAPK1MAP2K4MAPK6MAPKAPK3SRD5A2 | |
| SCHEMBL8400437 | 0.74 | ALPL (0.50) | PTGDR2 | |
| SCHEMBL11405709 | 0.73 | MAPK1 (0.44) | MAPK1MAP2K4MAPK6MAPKAPK3SRD5A2 | |
| SCHEMBL24987817 | 0.71 | DHODH (0.47) | MAPK1MAP2K4MAPK6MAPKAPK3SRD5A2 | |
| SCHEMBL8842879 | 0.71 | MKNK1 (0.48) | MAPK1MAP2K4MAPK6MAPKAPK3SRD5A2 | |
| SCHEMBL2467798 | 0.70 | PLAU (0.50) | MAPK1MAP2K4MAPK6MAPKAPK3SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948916-A | Arylthiadiazole derivative and antiviral agent containing the same | RATIONAL DRUG DESIGN LABORATORIES (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0785193-A1 | ARYLTHIADIAZOLE DERIVATIVE AND ANTIVIRAL AGENT CONTAINING THE SAME | Rational Drug Design Laboratories (JP) | 1997-07-23 | — | — | EP | disclosed |