SCHEMBL8401192

SCHEMBL8401192

COc1cc2cc3ccccc3cc2c(OC)c1S(=O)(=O)OCc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.47
HTR1A P08908 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
CYP19A1 P11511 5/20 0.40
PDE7A Q13946 1/20 0.40
PDE3A Q14432 1/20 0.40
PTGS2 P35354 1/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAPT P10636 3/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
NPC1 O15118 1/20 0.37
NFKB1 P19838 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970985 0.92 HTT (0.49) HTTHTR1AADRA1DADRA1AADRA1B
SCHEMBL335568 0.74 HTT (0.44) HTTHTR1AADRA1DADRA1AADRA1B
SCHEMBL30139585 0.74 HTT (0.44) HTTHTR1AADRA1DADRA1AADRA1B
SCHEMBL5950594 0.71 NQO1 (0.46) HTR1AMEN1KMT2AMAPTNPC1
SCHEMBL8400160 0.68 MEN1 (0.53) HTTCYP19A1MEN1KMT2AMAPT
SCHEMBL8970628 0.68 MMP1 (0.48) HTTCYP19A1PDE7AMEN1KMT2A
SCHEMBL13475516 0.67 MAOB (0.43) CYP19A1MEN1KMT2AMAPTNPC1
SCHEMBL8075081 0.67 S100A4 (0.45) HTTCYP19A1MEN1KMT2ARAB9A
SCHEMBL27724423 0.67 HTT (0.55) HTTCYP19A1MEN1KMT2AMAPT
SCHEMBL31233774 0.66 MEN1 (0.42) CYP19A1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540965-B1 Positive light sensitive composition and process for the formation of relief pattern BASF AG (DE) 1999-06-09 EP disclosed
US-5563022-A MIXTURE OF WATER INSOLUBLE ORGANIC BINDER HAVING ACID-LABILE ETHER, ESTER OR CARBONATE GROUPS OR BEING SOLUBLE IN ALKALINE SOLUTIONS, ORGANIC COMPOUND WHOSE SOLUBILITY IS INCREASED BY ACID, ARYLSULFONIC ESTER BASF AKTIENGESELLSCHAFT (DE) 1996-10-08 US disclosed