Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238566 | 0.79 | SRD5A2 (0.50) | CA1CA2 | |
| SCHEMBL1029790 | 0.78 | CA2 (0.61) | CA1CA2GSK3BPARP15PARP10 | |
| SCHEMBL536808 | 0.77 | TSHR (0.63) | CA1CA2RARBRARGTP53 | |
| SCHEMBL5808115 | 0.77 | CA1 (0.38) | CA1CA2RARBRARGGSK3B | |
| Bicarbonate SCHEMBL11402475 | 0.75 | TSHR (0.35) | CA1CA2RARBRARGTP53 | |
| SCHEMBL103281 | 0.75 | CA1 (0.37) | CA1CA2RARBRARGGSK3B | |
| SCHEMBL97267 | 0.75 | MAPT (0.50) | — | |
| SCHEMBL101544 | 0.75 | ALDH1A1 (0.45) | CA1CA2RARBRARGGSK3B | |
| SCHEMBL4757633 | 0.75 | PARP10 (0.52) | CA1CA2TSHRPARP15PARP10 | |
| SCHEMBL104811 | 0.74 | APP (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782563-B1 | POLYIODINATED COMPOUNDS, PREPARATION AND USE THEREOF IN X-RAY RADIOLOGY | GUERBET SA (FR) | 1999-06-23 | — | — | EP | claimed |
| EP-0782563-A1 | POLYIODINATED COMPOUNDS, PREPARATION AND USE THEREOF IN X-RAY RADIOLOGY | GUERBET S.A. (FR) | 1997-07-09 | — | — | EP | claimed |
| WO-1996009280-A1 | POLYIODINATED COMPOUNDS, PREPARATION AND USE THEREOF IN X-RAY RADIOLOGY | GUERBET S.A. (FR) | 1996-03-28 | — | — | WO | claimed |