Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727813 | 0.80 | ALOX5 (0.50) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| SCHEMBL4707186 | 0.79 | TRPM8 (0.60) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| SCHEMBL9095961 | 0.77 | SIGMAR1 (0.59) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| SCHEMBL8400925 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL6721242 | 0.74 | SIGMAR1 (0.54) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| SCHEMBL5813680 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| SCHEMBL18545425 | 0.73 | TRPM8 (0.50) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| SCHEMBL10651901 | 0.72 | ALDH1A1 (0.57) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| SCHEMBL4014610 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| SCHEMBL1468921 | 0.70 | CYP1A2 (0.56) | ALDH1A1MAPTTRPM8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |