Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | RARG | P13631 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397572 | 0.85 | RARA (0.53) | RARBRARGACHERARAKMT2A | |
| SCHEMBL8400865 | 0.84 | RARB (0.44) | RARBRARGRARAPTGDRPTGDR2 | |
| SCHEMBL8401653 | 0.84 | RARB (0.51) | RARBRARGACHERARAESR1 | |
| SCHEMBL8400759 | 0.81 | GLA (0.44) | RARBRARGACHERARAKMT2A | |
| SCHEMBL8399068 | 0.81 | TSHR (0.41) | RARBRARGACHERARAKMT2A | |
| SCHEMBL8401324 | 0.78 | GLA (0.36) | RARBRARGACHEKMT2ARECQL | |
| SCHEMBL252281 | 0.77 | RARB (0.49) | RARBRARGRARAKMT2ARECQL | |
| SCHEMBL8401581 | 0.76 | ACHE (0.39) | RARBRARGACHERARAKMT2A | |
| SCHEMBL8400764 | 0.76 | RARB (0.37) | RARBRARGACHERARAKMT2A | |
| SCHEMBL1681252 | 0.75 | KMT2A (0.55) | ACHEKMT2AESR1HIF1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |