Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | RARG | P13631 | 2/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 14/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401556 | 0.87 | RARA (0.49) | RARBRARGRARAOPRM1OPRD1 | |
| SCHEMBL8401696 | 0.84 | RARB (0.48) | RARBRARGRARAPTGDRPTGDR2 | |
| SCHEMBL8430349 | 0.83 | RARA (0.48) | RARBRARGRARAOPRM1OPRD1 | |
| SCHEMBL8400746 | 0.80 | VCAM1 (0.50) | RARBRARGOPRM1OPRD1OPRK1 | |
| SCHEMBL8401653 | 0.80 | RARB (0.51) | RARBRARGRARAPTGDRPTGDR2 | |
| SCHEMBL8397568 | 0.79 | RARB (0.34) | RARBRARGRARAOPRM1OPRD1 | |
| SCHEMBL8400744 | 0.78 | RARA (0.34) | RARBRARGRARAOPRM1OPRD1 | |
| SCHEMBL8397557 | 0.76 | VCAM1 (0.46) | RARBRARGRARAOPRM1OPRD1 | |
| SCHEMBL8432818 | 0.75 | OPRM1 (0.35) | RARBRARGRARAOPRM1OPRD1 | |
| SCHEMBL8431586 | 0.75 | OPRM1 (0.35) | RARBRARGRARAOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |