Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | HTR7 | P34969 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671906 | 0.89 | HDAC1 (0.35) | HDAC1ALDH1A1HTTATG4BMMP2 | |
| SCHEMBL7671911 | 0.89 | HDAC1 (0.35) | HDAC1ALDH1A1HTTATG4BMMP2 | |
| SCHEMBL7662536 | 0.86 | HDAC1 (0.34) | HDAC1ALDH1A1HTTATG4BMMP2 | |
| SCHEMBL2801383 | 0.86 | FAAH (0.43) | ALDH1A1L3MBTL1MAPTFAAH | |
| SCHEMBL888609 | 0.86 | FAAH (0.43) | ALDH1A1L3MBTL1MAPTFAAH | |
| SCHEMBL8405578 | 0.80 | PKM (0.50) | ALDH1A1HTTKMT2ALMNAMAPT | |
| SCHEMBL8064622 | 0.79 | MMP2 (0.35) | ALDH1A1HTTMMP2MMP9MMP8 | |
| SCHEMBL7664018 | 0.78 | LMNA (0.38) | HDAC1ALDH1A1HTTATG4BMEN1 | |
| SCHEMBL7664020 | 0.78 | LMNA (0.38) | HDAC1ALDH1A1HTTATG4BMEN1 | |
| SCHEMBL236739 | 0.77 | MMP2 (0.34) | ALDH1A1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |