SCHEMBL8401745

SCHEMBL8401745

CCCCCCCCCCCCCCCC(O)OCC(O)CO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.56
LMNA P02545 3/20 0.50
KDM4E B2RXH2 2/20 0.50
DUSP3 P51452 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP2D6 P10635 2/20 0.44
SPHK1 Q9NYA1 1/20 0.44
GMNN O75496 1/20 0.44
POLB P06746 1/20 0.44
THPO P40225 1/20 0.44
MTOR P42345 1/20 0.44
BLM P54132 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
CETP P11597 1/20 0.44
HTT P42858 1/20 0.44
UBE2N P61088 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17677400 1.00 USP2 (0.56) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL14511078 1.00 USP2 (0.56) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL16277114 1.00 USP2 (0.56) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL530879 1.00 USP2 (0.56) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL17237491 1.00 USP2 (0.56) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL3294751 0.98 USP2 (0.53) USP2LMNAKDM4EDUSP3MEN1
Sulfuric Acid SCHEMBL8349091 0.92 USP2 (0.49) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL7203820 0.90 DGKA (0.57) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL16254836 0.90 DGKA (0.57) USP2LMNAKDM4EDUSP3MEN1
SCHEMBL3395699 0.85 USP2 (0.56) USP2LMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2320863-B1 CLEANSING COMPOSITION KAO GERMANY GMBH (DE) 2018-05-16 EP claimed
EP-2320855-B1 CONDITIONING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2017-12-27 EP claimed
EP-2320862-B1 CLEANSING COMPOSITION KAO GERMANY GMBH (DE) 2016-04-27 EP claimed
EP-2320856-B1 CONDITIONING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2015-11-11 EP claimed
US-12031006-B2 Use of polyolethers for producing porous plastic coatings EVONIK OPERATIONS GMBH (DE) 2024-07-09 US disclosed
CN-114901237-A Oil-in-water emulsion cosmetic LVMH研究公司 2022-08-12 CN disclosed
US-20200207938-A1 USE OF POLYOLETHERS FOR PRODUCING POROUS PLASTIC COATINGS EVONIK OPERATIONS GMBH (DE) 2020-07-02 US disclosed
US-9937140-B2 Branched chain amino acids: formulations and methods of treatment UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2018-04-10 US disclosed
CN-107029229-A The method for preparing vesica and the preparation being generated by it 变异生物技术公司 2017-08-11 CN disclosed
US-20150126604-A1 BRANCHED CHAIN AMINO ACIDS: FORMULATIONS AND METHODS OF TREATMENT NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-05-07 US disclosed
US-6001376-A COSMETIC COMPOSITIONS FOR THE TREATMENT OF KERATINOUS SUBSTANCES AND FOR BUCCODENTAL HYGIENE L'OREAL (FR) 1999-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126604-A1 BRANCHED CHAIN AMINO ACIDS: FORMULATIONS AND METHODS OF TREATMENT GLS, BCAT2, ARG2 USP2 1372/4885LMNA 863/4885KDM4E 3126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.