Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L11 | O43521 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399955 | 0.79 | RORC (0.43) | BCL2L11BCL2L1SMN1; SMN2CNR2GAA | |
| SCHEMBL15100553 | 0.78 | MAPT (0.47) | SMN1; SMN2NPC1CNR2GAALMNA | |
| SCHEMBL8403980 | 0.74 | CA1 (0.45) | GAALMNAHTTMEN1KMT2A | |
| SCHEMBL322168 | 0.74 | CTSD (0.62) | SMN1; SMN2NPC1CNR2RAB9ALMNA | |
| SCHEMBL29658169 | 0.74 | CTSD (0.62) | SMN1; SMN2NPC1CNR2RAB9ALMNA | |
| SCHEMBL13931838 | 0.73 | L3MBTL1 (0.63) | BCL2L11BCL2L1MCL1SMN1; SMN2GAA | |
| SCHEMBL8182920 | 0.73 | MAPK14 (0.56) | SMN1; SMN2NPC1CNR2RAB9AGAA | |
| SCHEMBL27789892 | 0.72 | CTSD (0.60) | SMN1; SMN2NPC1CNR2RAB9ALMNA | |
| SCHEMBL8174964 | 0.71 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1CNR2RAB9AGAA | |
| SCHEMBL29262352 | 0.71 | LMNA (0.55) | SMN1; SMN2NPC1RAB9AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952368-A | AN INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE, ANTIINFLAMMATORY AND ANALGESIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1999-09-14 | — | — | US | disclosed |