SCHEMBL84022

SCHEMBL84022

Ic1c[nH]c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.54
GPR84 Q9NQS5 3/20 0.52
MEN1 O00255 2/20 0.52
CYP3A4 P08684 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 1/20 0.52
AHR P35869 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
IMPDH2 P12268 4/20 0.48
NR4A2 P43354 1/20 0.48
PRKD3 O94806 1/20 0.48
CCNB2 O95067 1/20 0.48
CCNE2 O96020 1/20 0.48
ABL1 P00519 1/20 0.48
PRKCG P05129 1/20 0.48
PRKCB P05771 1/20 0.48
CDK1 P06493 1/20 0.48
PIM1 P11309 1/20 0.48
CDK4 P11802 1/20 0.48
CCNB1 P14635 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29472310 1.00 ATM (0.54) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL28090451 0.86 GPR84 (0.45) ATMGPR84MEN1CYP3A4KMT2A
Thiourea SCHEMBL8083677 0.84 IDO1 (0.51) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL1072588 0.82 ATM (0.50) ATMGPR84MEN1CYP3A4KMT2A
Propionic Acid SCHEMBL19133597 0.82 ADAM17 (0.50) GPR84MEN1KMT2AMAPTNR4A2
SCHEMBL28839060 0.75 ATM (0.54) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL1202543 0.74 IMPDH2 (0.63) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL28377762 0.73 NR4A2 (0.81) CYP3A4MAPTIMPDH2NR4A2PRKD3
SCHEMBL2012509 0.72 ATM (0.56) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL2953261 0.72 ATM (0.56) ATMGPR84MEN1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119161383-A Multidentate nitrogen-phosphine ligand, preparation method and application thereof 万华化学集团股份有限公司 2024-12-20 CN claimed
CN-116574139-A NHCs-Pd complex with ultraviolet-visible light controllable isomerization and catalytic activity and preparation method thereof 上海师范大学 2023-08-11 CN claimed
CN-113956242-B Photosensitizer for inducing immunogenic cell death and preparation method and application thereof 天津工业大学 2022-09-02 CN claimed
CN-112574092-B Green novel method for preparing 2-diaryl methyl substituted indole compound 湖南理工学院 2022-08-30 CN claimed
CN-114583051-A Photochromic organic field effect transistor 西北工业大学 2022-06-03 CN claimed
CN-113956242-A Photosensitizer for inducing immunogenic cell death and preparation method and application thereof 天津工业大学 2022-01-21 CN claimed
CN-112574092-A Green novel method for preparing 2-diaryl methyl substituted indole compound 湖南理工学院 2021-03-30 CN claimed
CN-110105342-A Detect the fluorescence probe of reduced nicotinamide adenine dinucleotide and its phosphate and the preparation method and application of the fluorescence probe 周口师范学院 2019-08-09 CN claimed
CN-109749734-A A kind of Ratiometric fluorescent probe can detecte sulfite ion and application 泰山医学院 2019-05-14 CN claimed
CN-109206440-A Spirooxazine class photochromic compound 苏州健雄职业技术学院 2019-01-15 CN claimed
CN-107207433-A New organic compound, the near infrared fluorescent contrast agent containing the compound and the method for preparing nano particle contrast agent 车医科学大学校产学协力团 2017-09-26 CN claimed
CN-106588750-A Disposable and rapid octadecyl-chain-containing targeting mitochondrion fluorescent probe and application thereof 山东大学 2017-04-26 CN claimed
CN-106518749-A Rate type difunctional fluorescence molecular probe for detecting HSO4- ions, SO2 and derivatives thereof 湖南师范大学 2017-03-22 CN claimed
CN-106496197-A A kind of Fluorescence Increasing type quick detection sulfurous acid hydrogen radical ion or the synthesis and application of sulfite ion fluorescent molecular probe 湖南师范大学 2017-03-15 CN claimed
CN-105777607-A Triphenylamine bis-indolyl iodised salt as well as synthesis method and application thereof 山西大学 2016-07-20 CN claimed
CN-103260651-A Silica nanoparticles doped with multiple dyes featuring highly efficient energy transfer and tunable stokes-shift UNI DI BOLOGNA 2013-08-21 CN claimed
CN-103224503-A Novel method for compounding naphtho-spirooxazine type photochromic compound UNIV CENTRAL SOUTH 2013-07-31 CN claimed
CN-103113283-A Method for preparing hemicyanine plastocyanin temperature-sensitive molecular optical probe containing electron-donating group UNIV TIANJIN TECHNOLOGY 2013-05-22 CN claimed
CN-103113282-A Preparation method for electrondrawing group containing semi-cyanine temperature-sensitive molecular optical probe UNIV TIANJIN TECHNOLOGY 2013-05-22 CN claimed
CN-1583755-A Photochromic spiro [ indoline-phenanthroline oxazine ] compound and preparation method and application thereof PHYSICS & CHEMISTRY INST CHINE (CN) 2005-02-23 CN claimed