Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12971340 | 0.88 | NOS2 (0.35) | NOS2ARIKBKBALDH1A1CYP1A2 | |
| SCHEMBL5490266 | 0.84 | NOS2 (0.34) | NOS2ARNOS3NOS1HMGCR | |
| SCHEMBL3804549 | 0.84 | NOS2 (0.36) | NOS2ARIKBKBALDH1A1NOS3 | |
| SCHEMBL9690320 | 0.83 | NOS2 (0.33) | NOS2ARALDH1A1NOS3NOS1 | |
| SCHEMBL2317715 | 0.79 | NOS2 (0.35) | NOS2IKBKBALDH1A1NOS3NOS1 | |
| SCHEMBL3802566 | 0.78 | HTT (0.39) | NOS2ARIKBKBALDH1A1NOS3 | |
| SCHEMBL3801329 | 0.77 | KDM4E (0.39) | NOS2ARIKBKBALDH1A1NOS3 | |
| SCHEMBL27468200 | 0.77 | NOS3 (0.32) | NOS2ARIKBKBNOS3NOS1 | |
| SCHEMBL3799895 | 0.77 | NOS2 (0.40) | NOS2IKBKBALDH1A1CYP1A2ALOX15 | |
| SCHEMBL19972018 | 0.77 | NOS2 (0.32) | NOS2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170260319-A1 | HYBRID NOVOLAC POLYUREA/POLYURETHANE | PPG INDUSTRIES OHIO, INC. | 2017-09-14 | — | — | US | disclosed |
| WO-2013009372-A1 | PHOSPHORUS-CONTAINING SECONDARY AMINE COMPOUNDS | HUNTSMAN PETROCHEMICAL LLC (US) | 2013-01-17 | — | — | WO | disclosed |
| US-8212078-B2 | Making chain extenders with slower cure rates; reacting a ketone and/or aldehyde with a primary amine in the presence of an acidic ion exchange resin and hydrogenation agent; making diimine same way but excluding hydrogenation agent; e.g. N,N'-di-5-nonyl-isophoronediamine | ALBEMARLE CORPORATION (US) | 2012-07-03 | — | — | US | disclosed |
| US-8143365-B2 | Formulations for reaction injection molding and for spray systems | ALBEMARLE CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-8080626-B2 | Chain extenders | ALBEMARLE CORPORATION (US) | 2011-12-20 | — | — | US | disclosed |
| US-7964695-B2 | Chain extenders | ALBEMARLE CORPORATION (US) | 2011-06-21 | — | — | US | disclosed |
| US-20110137005-A1 | Chain Extenders | ALBEMARLE CORPORATION (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2010101560-A1 | BIS[(ALKYLAMINO)ALKYL]AMINES | ALBEMARLE CORPORATION (US) | 2010-09-10 | — | — | WO | disclosed |
| US-7767858-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100160592-A1 | Formulations For Reaction Injection Molding And For Spray Systems | ALBEMARLE CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2008112636-A1 | CHAIN EXTENDERS | ALBEMARLE CORPORATION (US) | 2008-09-18 | — | — | WO | disclosed |
| US-20080194788-A1 | Diimines and Secondary Diamines | ALBEMARLE CORPORATION (US) | 2008-08-14 | — | — | US | disclosed |
| WO-2008086437-A1 | FORMULATIONS FOR REACTION INJECTION MOLDING AND FOR SPRAY SYSTEMS | ALBEMARLE CORPORATION (US) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008039571-A1 | DIAMINE CHAIN EXTENDER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2008039715-A1 | CHAIN EXTENDERS | ALBEMARLE CORPORATION (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20080033210-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080004406-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-01-03 | — | — | US | disclosed |
| US-20070270566-A1 | Chain Extenders | ALBEMARLE CORPORATION (US) | 2007-11-22 | — | — | US | disclosed |
| US-7288677-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2007-10-30 | — | — | US | disclosed |
| US-20060217567-A1 | Diimines and secondary diamines | ALBEMARLE CORPORATION | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004406-A1 | DIIMINES AND SECONDARY DIAMINES | DDT, DDC, AOC1 | NOS2 366/4885AR 1890/4885IKBKB 1874/4885 |
| US-20070270566-A1 | Chain Extenders | DDC, PARG, ODC1 | NOS2 1696/4885AR 761/4885IKBKB 2253/4885 |
| US-20080033210-A1 | DIIMINES AND SECONDARY DIAMINES | DDT, DDC, AOC1 | NOS2 366/4885AR 1890/4885IKBKB 1874/4885 |
| US-20080194788-A1 | Diimines and Secondary Diamines | DDT, DDC, AOC1 | NOS2 586/4885AR 1669/4885IKBKB 1603/4885 |
| US-20060217567-A1 | Diimines and secondary diamines | DDT, DDC, AOC1 | NOS2 366/4885AR 1890/4885IKBKB 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.