SCHEMBL8402960

SCHEMBL8402960

CN(CCc1ccccc1)Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 5/20 0.71
▸ CARM1 Q86X55 1/20 0.67
▸ PRMT6 Q96LA8 1/20 0.67
▸ PRMT8 Q9NR22 1/20 0.67
▸ TAAR1 Q96RJ0 1/20 0.64
▸ AOC3 Q16853 1/20 0.59
▸ ALDH1A1 P00352 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ MEN1 O00255 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ USP2 O75604 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ MAOA P21397 1/20 0.53
▸ MAOB P27338 1/20 0.53
▸ PYCR1 P32322 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6538284 0.96 SIGMAR1 (0.67) SIGMAR1CARM1PRMT6PRMT8TAAR1
SCHEMBL21231364 0.92 ALDH1A1 (0.65) SIGMAR1CARM1PRMT6PRMT8TAAR1
SCHEMBL13222367 0.90 KDM4E (0.62) SIGMAR1CARM1PRMT6PRMT8TAAR1
Hydrochloric Acid SCHEMBL3330624 0.90 SIGMAR1 (0.61) SIGMAR1CARM1PRMT6PRMT8TAAR1
SCHEMBL4422628 0.89 SIGMAR1 (0.59) SIGMAR1CARM1PRMT6PRMT8TAAR1
SCHEMBL9720765 0.89 SIGMAR1 (0.59) SIGMAR1CARM1PRMT6PRMT8TAAR1
SCHEMBL12018644 0.89 SIGMAR1 (0.59) SIGMAR1CARM1PRMT6PRMT8TAAR1
SCHEMBL7599299 0.89 CARM1 (0.59) SIGMAR1CARM1PRMT6PRMT8TAAR1
SCHEMBL3148258 0.89 CARM1 (0.59) SIGMAR1CARM1PRMT6PRMT8TAAR1
SCHEMBL7055109 0.88 CARM1 (0.75) SIGMAR1CARM1PRMT6PRMT8TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4488282-A Damping material RCA CORPORATION (US) 1984-12-11 — — US claimed
JP-11043535-A — — None — — JP disclosed
EP-4257593-A1 CHIRAL MULTIDENTATE LIGAND AND USE THEREOF IN ASYMMETRIC HYDROGENATION SHENZHEN CATALYS TECHNOLOGY CO., LTD. (CN) 2023-10-11 — — EP disclosed
US-20220111367-A1 HYDROGENATION CATALYST FOR USE IN HYDROGENATING AMIDE COMPOUND AND METHOD FOR PRODUCING AMINE COMPOUND USING SAME OSAKA UNIVERSITY (JP) 2022-04-14 — — US disclosed
CN-113773598-A Preparation method of carbon-based composite material 宁波信远炭材料股份有限公司 2021-12-10 — — CN disclosed
CN-107416859-A A kind of preparation method and application of step hole Beta molecular sieves 福州大学 2017-12-01 — — CN disclosed
CN-103771439-A Method for preparing Beta zeolite molecular sieve from diatomite JILIN UNIVERSITY OF CHEMICAL TECHNOLOGY 2014-05-07 — — CN disclosed
CN-102502684-B Beta zeolite molecular sieve synthesis method UNIV DALIAN TECH 2013-05-08 — — CN disclosed
CN-102107879-A Method for synthesizing Beta zeolite molecular sieve UNIV DALIAN TECH 2011-06-29 — — CN disclosed
EP-1757591-A1 CINNAMIDE COMPOUND Eisai R&D Management Co., Ltd. (JP) 2007-02-28 — — EP disclosed
JP-H1143535-A OLEFIN-BASED RESIN AND TONER FOR ELECTROPHOTOGRAPHY USING THE SAME TOMOEGAWA PAPER CO LTD 1999-02-16 — — JP disclosed
CN-1198404-A Zeolite synthesizing method RES INST YANSHAN PETROCHEMICAL (CN) 1998-11-11 — — CN disclosed
EP-0159040-B1 PYRIDINE DERIVATIVES AND PRODUCTION THEREOF NIPPON SHINYAKU COMPANY, LIMITED (JP) 1992-12-09 — — EP disclosed
US-5036059-A Hypotensive agents, vasodilators NIPPON SHINYAKU COMPANY, LIMITED (JP) 1991-07-30 — — US disclosed
US-4960939-A Process for the preparation of 3,4-di-methoxy-N-methyl-phenethylamine FARMOS-YHTYMA OY (FI) 1990-10-02 — — US disclosed
EP-0121117-B1 DERIVATIVES OF DIHYDROPYRIDINE AND PRODUCTION THEREOF NIPPON SHINYAKU COMPANY, LIMITED (JP) 1989-08-30 — — EP disclosed
EP-0129383-B1 PROCESS FOR THE PREPARATION OF 3,4-DI-ISOBUTYRYLOXY-N-METHYL-PHENETHYLAMINE Farmos-Yhtyma Oy (FI) 1988-12-28 — — EP disclosed
US-4535073-A VASODILATION NIPPON SHINYAKU CO LIMITED (JP) 1985-08-13 — — US disclosed
EP-0129383-A1 Process for the preparation of 3,4-di-isobutyryloxy-N-methyl-phenethylamine Farmos-Yhtyma Oy (FI) 1984-12-27 — — EP disclosed
US-4488282-A Damping material RCA CORPORATION (US) 1984-12-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220111367-A1 HYDROGENATION CATALYST FOR USE IN HYDROGENATING AMIDE COMPOUND AND METHOD FOR PRODUCING AMINE COMPOUND USING SAME SUV39H2, SUV39H1, HRH3 SIGMAR1 1530/4885CARM1 218/4885PRMT6 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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