Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018644 | 1.00 | SIGMAR1 (0.59) | SIGMAR1KDM4ECARM1PRMT6PRMT8 | |
| SCHEMBL579483 | 0.91 | ACHE (0.58) | SIGMAR1KDM4ECARM1PRMT6PRMT8 | |
| SCHEMBL8402960 | 0.89 | SIGMAR1 (0.71) | SIGMAR1CARM1PRMT6PRMT8MEN1 | |
| SCHEMBL4422628 | 0.86 | SIGMAR1 (0.59) | SIGMAR1CARM1PRMT6PRMT8MEN1 | |
| SCHEMBL21231364 | 0.85 | ALDH1A1 (0.65) | SIGMAR1CARM1PRMT6PRMT8MEN1 | |
| SCHEMBL6538284 | 0.85 | SIGMAR1 (0.67) | SIGMAR1CARM1PRMT6PRMT8MEN1 | |
| SCHEMBL13222367 | 0.84 | KDM4E (0.62) | SIGMAR1KDM4ECARM1PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL3330624 | 0.84 | SIGMAR1 (0.61) | SIGMAR1CARM1PRMT6PRMT8MEN1 | |
| SCHEMBL3148258 | 0.82 | CARM1 (0.59) | SIGMAR1CARM1PRMT6PRMT8MEN1 | |
| SCHEMBL7599299 | 0.82 | CARM1 (0.59) | SIGMAR1CARM1PRMT6PRMT8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |