SCHEMBL8403262

SCHEMBL8403262

CC(O)CN1CC(=O)OC(C)C1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
PRMT5 O14744 3/20 0.33
WDR77 Q9BQA1 3/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2011969 0.77 SMN1; SMN2 (0.43) SMN1; SMN2CA1CA9
SCHEMBL2011964 0.77 SMN1; SMN2 (0.43) SMN1; SMN2CA1CA9
SCHEMBL2014044 0.77 SMN1; SMN2 (0.43) SMN1; SMN2CA1CA9
SCHEMBL11654410 0.73 SMN1; SMN2 (0.36) SMN1; SMN2CA1CA9
SCHEMBL4618370 0.72 GRM2 (0.44)
SCHEMBL7946995 0.72 SMN1; SMN2 (0.39) SMN1; SMN2CA1CA9
SCHEMBL8421032 0.72 MAPK1 (0.47) SMN1; SMN2MAPK1KDM4EALDH1A1POLB
SCHEMBL8421030 0.72 MAPK1 (0.47) SMN1; SMN2MAPK1KDM4EALDH1A1POLB
SCHEMBL8421034 0.72 MAPK1 (0.47) SMN1; SMN2MAPK1KDM4EALDH1A1POLB
SCHEMBL8827052 0.70 PTGS1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230124955-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-04-20 US disclosed
US-20200330501-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-10-22 US disclosed
US-10682374-B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof MASSACHUSETTS INTSTITUTE OF TECHNOLOGY (US) 2020-06-16 US disclosed
US-20190076462-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-03-14 US disclosed
US-20180036333-A9 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-02-08 US disclosed
US-20170165290-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-06-15 US disclosed
US-5985803-A COMPRISING WATER AND ADDITIVE COMPRISING PHOSPHONATE CARBOXYLIC ESTER, AND RUST INHIBITOR COMPRISING AMINE ACID SALT OR AMIDE, NITROGEN-CONTAINING, PHOSPHORUS-FREE CARBOXYLIC COMPOSITION, AMINE, OR ALKOXYLATED AMINE THE LUBRIZOL CORPORATION (US) 1999-11-16 US disclosed
EP-0922753-A2 Polyethoxylated alcohol-based phosphonates for metal working lubricants The Lubrizol Corporation (US) 1999-06-16 EP disclosed
US-5674819-A POLYMER FROM ALPHA-OLEFIN MONOMERS, ETHYLENE, A NON-CONJUGATED DIENE AND AN UNSATURATED DICARBOXYLIC ACID MONOMERS; REDUCTION OF SOOT-INDUCED VISCOSITY; DIESEL ENGINES THE LUBRIZOL CORPORATION (US) 1997-10-07 US disclosed
EP-0778333-A2 Carboxylic compositions, derivatives, lubricants, fuels and concentrates The Lubrizol Corporation (US) 1997-06-11 EP disclosed
US-4615813-A DRILLING FLUIDS THE LUBRIZOL CORPORATION (US) 1986-10-07 US disclosed
EP-0187756-A1 ALKENYL-SUBSTITUTED CARBOXYLIC ACYLATING AGENT/HYDROXY TERMINATED POLYOXYALKYLENE REACTION PRODUCTS AND AQUEOUS SYSTEMS CONTAINING SAME The Lubrizol Corporation (US) 1986-07-23 EP disclosed
US-4582543-A WITH AN OVERBASED COMPOUND-CORROSION INHIBITING COATING THE LUBRIZOL CORPORATION (US) 1986-04-15 US disclosed
WO-1986000081-A1 ALKENYL-SUBSTITUTED CARBOXYLIC ACYLATING AGENT/HYDROXY TERMINATED POLYOXYALKYLENE REACTION PRODUCTS AND AQUEOUS SYSTEMS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1986-01-03 WO disclosed
US-4468339-A AND SOLUBILIZER WHICH IS REACTION OF CARBOXYLIC ACID ACYLATING AGENT WITH HYDROCARBON SUBSTITMENT AND HYDROXYAMINE THE LUBRIZOL CORPORATION (US) 1984-08-28 US disclosed
US-4448703-A Carboxylic solubilizer/surfactant combinations and aqueous compositions containing same THE LUBRIZOL CORPORATION (US) 1984-05-15 US disclosed
US-4447348-A Carboxylic solubilizer/surfactant combinations and aqueous compositions containing same THE LUBRIZOL CORPORATION (US) 1984-05-08 US disclosed
EP-0084966-A2 Aqueous compositions containing overbased materials The Lubrizol Corporation (US) 1983-08-03 EP disclosed
US-4368133-A Aqueous systems containing nitrogen-containing, phosphorous-free carboxylic solubilizer/surfactant additives THE LUBRIZOL CORPORATION (US) 1983-01-11 US disclosed
US-4234435-A Novel carboxylic acid acylating agents, derivatives thereof, concentrate and lubricant compositions containing the same, and processes for their preparation THE LUBRIZOL CORPORATION (US) 1980-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200330501-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 SMN1; SMN2 2337/4885PRMT5 58/4885WDR77 295/4885
US-20230124955-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 SMN1; SMN2 2337/4885PRMT5 58/4885WDR77 295/4885
US-20170165290-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 SMN1; SMN2 2337/4885PRMT5 58/4885WDR77 295/4885
US-20190076462-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 SMN1; SMN2 2337/4885PRMT5 58/4885WDR77 295/4885
US-20180036333-A9 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 SMN1; SMN2 2337/4885PRMT5 58/4885WDR77 295/4885
US-10682374-B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof APLNR, NPPA, ARGLU1 SMN1; SMN2 2337/4885PRMT5 58/4885WDR77 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.