Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 11/20 | 0.48 |
| ▸ | CA1 | P00915 | 10/20 | 0.48 |
| ▸ | CA12 | O43570 | 9/20 | 0.48 |
| ▸ | CA9 | Q16790 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840932 | 0.87 | TDP1 (0.51) | TDP1CYP1A2CA2CA1CA12 | |
| SCHEMBL3222486 | 0.85 | CYP1A2 (0.57) | TDP1CYP1A2CA2CA1CA12 | |
| SCHEMBL14214100 | 0.85 | CYP1A2 (0.57) | TDP1CYP1A2MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14845574 | 0.84 | TDP1 (0.48) | TDP1CYP1A2CA2CA1CA12 | |
| SCHEMBL842390 | 0.78 | TDP1 (0.54) | TDP1CYP1A2CA2CA1CA12 | |
| SCHEMBL824444 | 0.77 | RAB9A (0.55) | TDP1CYP1A2CA2CA1CA12 | |
| SCHEMBL824436 | 0.77 | RAB9A (0.55) | TDP1CYP1A2CA2CA1CA12 | |
| SCHEMBL12874082 | 0.76 | CYP1A2 (0.59) | CYP1A2LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL840742 | 0.75 | TDP1 (0.50) | TDP1CYP1A2CA1LMNAMAPT | |
| SCHEMBL824409 | 0.75 | CYP1A2 (0.59) | CYP1A2LMNAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120308608-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-12-06 | — | — | US | disclosed |
| US-20120308608-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-12-06 | — | — | US | disclosed |
| US-8142863-B2 | Color liquid crystal display and compensation panel | Crysoptix, KK (JP) | 2012-03-27 | — | — | US | disclosed |
| WO-2011094693-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | MOUNT SINAI SCHOOL OF MEDICINE (US) | 2011-08-04 | — | — | WO | disclosed |
| US-20090268136-A1 | Color Liquid Crystal Display and Compensation Panel | CRYSOPTIX KK (JP) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120308608-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | IRF3, IFNG, IFNAR1 | TDP1 3291/4885CYP1A2 4337/4885CA2 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.